Nnamdi Azikiwe University

Monkeypox Virus in Nigeria: Infection Biology, Epidemiology, and Evolution

Monkeypox is a zoonotic disease caused by monkeypox virus (MPXV), which is a member of orthopoxvirus genus. The reemergence of MPXV in 2017 (at Bayelsa state) after 39 years of no reported case in Nigeria, and the export of travelers' monkeypox (MPX) from Nigeria to other parts of the world, in 2018 and 2019, respectively, have raised concern that MPXV may have emerged to occupy the ecological and immunological niche vacated by smallpox virus. This review X-rays the current state of knowledge pertaining the infection biology, epidemiology, and evolution of MPXV in Nigeria and worldwide, especially with regard to the human, cellular, and viral factors that modulate the virus transmission dynamics, infection, and its maintenance in nature. This paper also elucidates the role of recombination, gene loss and gene gain in MPXV evolution, chronicles the role of signaling in MPXV infection, and reviews the current therapeutic options available for the treatment and prevention of MPX. Additionally, genome-wide phylogenetic analysis was undertaken, and we show that MPXV isolates from recent 2017 outbreak in Nigeria were monophyletic with the isolate exported to Israel from Nigeria but do not share the most recent common ancestor with isolates obtained from earlier outbreaks, in 1971 and 1978, respectively. Finally, the review highlighted gaps in knowledge particularly the non-identification of a definitive reservoir host animal for MPXV and proposed future research endeavors to address the unresolved questions.

High-fidelity simulation and nursing students’ anxiety and self-confidence: A systematic review

BACKGROUND: As a complementary teaching pedagogy, high-fidelity simulation remains as an effective form of simulation modality. Empirical evidence has additionally shown high-fidelity simulation (HFS) to be an effective contributor to students' learning outcomes. PURPOSE: This paper critically appraised existing scientific articles that covered the influence of utilizing HFS on the effects of nursing students' anxiety and self-confidence during undergraduate nursing education. METHODS: This was a systematic review of scientific articles conducted from 2007 to 2017 on the topic of the influence of using HFS on students' self-confidence and anxiety. The literature of six electronic databases (Proquest, SCOPUS, MEDLINE, PubMed Central, CINAHL, and PsychINFO) was reviewed. RESULTS: Following the literature search, 35 articles were selected. This review provides updated evidence on the efficacy of HFS in reducing anxiety and enhancing self-confidence among nursing students when performing nursing duties or managing patients. Moreover, this review highlights the need for more research that examines the impact of HFS on students' anxiety. CONCLUSION: As this form of simulation is found to be effective in the enhancement of nursing student self-confidence and the reduction of their anxiety when caring for patients and/or employing nursing skills, the inclusion of simulation-based activities in all clinical nursing courses is vital.

National surgical, obstetric, anaesthesia and nursing plan, Nigeria

Recent evidence suggests that strengthening surgical care within existing health systems will strengthen the overall health-care system. However, Nigeria's national strategic health development plan 2018-2022 placed little emphasis on surgical care. To address the gap, we worked with professional societies and other partners to develop the national surgical, obstetric, anaesthesia and nursing plan 2019-2023. The aim was to foster actions to prioritize surgical care for the achievement of universal health coverage. In addition to creating a costed strategy to strengthen surgical care, the plan included children's surgery and nursing: two key aspects that have been neglected in other national surgical plans. Pilot implementation of the plan began in 2020, supported by a nongovernmental organization with experience in surgical care in the region. We have created specific entry points to facilitate the pilot implementation. In the pilot, an electronic surgery registry has been created; personnel are being trained in life support; nurses are being trained in safe perioperative care; biomedical technicians and sterile supplies nurses are being trained in surgical instrument repair and maintenance; and research capacity is being strengthened. In addition, the mainstream media are being mobilized to improve awareness about the plan among policy-makers and the general population. Another development partner is interested in providing support for paediatric surgery, and a children's hospital is being planned. As funding is a key challenge to full implementation, we need innovative domestic funding strategies to support and sustain implementation.

A review of MRI studies in Africa with special focus on quantitative MRI: Historical development, current status and the role of medical physicists

Influence of Family Background on Academic Achievement of Secondary School Biology Students in Anambra State

The study sought to find out how family background of students in Anambra State, Nigeria influences their academic achievement in senior secondary school Biology. A survey design was adopted for the study. Five hundred and forty-six (546) Senior Secondary Two (SS2) biology students were drawn by simple random sampling from 14 schools within Awka, Nnewi and Onitsha Education Zones, in Anambra State. Three research questions and four hypotheses guided the study. Data were collected using a researcher constructed questionnaire and students‟ SS1 and SS2 school results. The results revealed that family structure, parents‟ occupation and educational level of parents, did not have significant influence on students‟ achievement in biology. Based on the findings, the paper concludes that family background did not have much influence on students‟ achievement in science (biology) as against what most previous studies portrayed. Researches should therefore focus on other possible factors that contribute to students‟ poor performance in Biology and science generally in order to find lasting solution to the problem. Some recommendations were also made.Keywords: Biology, polygamous, monogamous, occupation, educational level, academic achievement.

A Survey of Biology Teachers Use of Activity-Oriented, Laboratory Practical Exercises to Promote Functional Biology Education

A major goal of science education is fostering students’ intellectual competencies such as independent learning, problem-solving, decision-making and critical thinking. This goal can only be achieved when students are actively involved in the teaching-learning process through activity-based, practical-oriented instructional methods involving the use of laboratories. This study therefore, investigated the extent to which the biology teachers employ activity-oriented, laboratory/practical instructional methods in order to improve the learning outcome of their students. The descriptive survey involved 73 Biology teachers randomly selected from all the six education zones of Anambra state, Nigeria. Four research questions were posed and four hypotheses were formulated to guide the conduct of the study. A 32-item structured questionnaire which has reliability co-efficient of 0.82 was used to collect data. Data were analyzed using mean, standard deviation and t-tests. Results show that Biology teachers adopt practical-oriented strategies in teaching biology, conduct practical activities to a high extent, and perceive practical exercises as essential to effective teaching and learning of the subject. Provision of adequate number of laboratory materials, employment of adequate number of biology teachers, making provision for well designed laboratory activities in the curriculum and training of teachers on how to effectively combine theory with practical are some of the strategies that will encourage biology teachers to conduct practical lessons. There was no significant difference between male and female biology teachers in their responses to the different aspects investigated. Based on these findings, some recommendations were made that include that curriculum designers should incorporate guides for practical activities that go with each topic in the curriculum so as to encourage the teachers to teach theory with practical as a unified whole to increase students’ understanding and internalization of the facts and ideas taught.

Oilseed Crops - Uses, Biology and Production

This book contains six comprehensive chapters addressing various aspects of oilseed crop biology, production and use. The contributions summarize recent findings on oilseed crop responses to the environment, with a particular focus on rapeseed biology and stress tolerance. This book will be useful for undergraduate and graduate students, teachers, and researchers, particularly in the fields of agronomy and crop science.

Biology Learning Innovation Using Booklet Media

Purpose of the study: This study aims to develop booklet-based learning media for the 11th grade Biology subject, as well as to measure the level of validity and effectiveness of the media in improving the learning of Biology for 11th grade students. Methodology: This study uses a development research method with a 4-D approach (define, design, development, disseminate). The subjects of the study were students of class 11 MIA I at Islamic high school Madani Pao-Pao (24 students) and State Islamic High School 1 Makassar (35 students). Data collection techniques were through observation, interviews, and documents. Data were analyzed qualitatively with descriptive presentation. Main Findings: The results of the study showed that the developed booklet-based learning media received validation with an average of 3.5, which means it is very valid. Field trials at Islamic high school Madani Pao-Pao and State Islamic High School 1 Makassar showed that this media was effective, with an average implementation value of 3.6 and 3.1, which were included in the good and very good categories. Positive responses from teachers and students stated that booklets helped increase learning motivation and facilitated understanding of the material. Novelty/Originality of this study: The novelty of this research lies in the development of booklet-based learning media that integrates material summaries with relevant images and quizzes to train students' critical thinking skills. This media is also designed to increase learning motivation through an attractive and practical display, and is adjusted to the curriculum and needs of Islamic high school students.