Olabisi Onabanjo University
NG
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Public research profiles associated with Olabisi Onabanjo University.
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Nursing in the Digital Age: Harnessing telemedicine for enhanced patient care
Telemedicine has emerged as a transformative force in contemporary healthcare, reshaping nursing practice across various specialties. This narrative review explored the role, challenges, and ethical considerations associated with telemedicine in nursing practice. Also, it emphasizes telemedicine’s impact on patient care, the evolution of nursing workflows, and future directions for implementation. A comprehensive narrative review was conducted, drawing upon primary research articles, systematic reviews, and policy documents published between 2010 and 2023. The search was carried out using electronic databases, including PubMed, ScienceDirect, CINAHL, and Google Scholar, employing keywords such as "telemedicine," "nursing practice," "patient care," and "ethical considerations." Eligible studies were critically appraised for relevance and rigor. Data synthesis included the identification of key themes, trends, and exemplary instances of telemedicine utilization in nursing practice. The review revealed a multifaceted role of telemedicine in nursing practice. Teletriage and remote patient monitoring were instrumental in reducing emergency department overcrowding and improving patient triage accuracy. Teleconsultations and virtual visits facilitated patient-provider interactions, while telepsychiatry addressed the growing demand for mental health support. Tele-education emerged as a vital tool for ongoing professional development among nurses. Moreover, telemedicine effectively reached rural and underserved populations, addressing healthcare disparities. Ethical considerations, such as patient privacy, informed consent, and data security, emerged as significant challenges in telemedicine. As telemedicine continues to evolve, nurses should remain adaptable, actively engaging with emerging technologies and interdisciplinary teams. Furthermore, healthcare organizations, policymakers, and nursing associations/regulatory bodies should collaborate to establish clear ethical and legal guidelines. These efforts will ensure the continued growth of telemedicine in nursing practice, ultimately enhancing patient outcomes and expanding access to quality healthcare services. • Telemedicine correlates with improved patient outcomes and higher satisfaction rates. • Nurses are pivotal in teletriage and remote patient monitoring initiatives. • Teleconsultations streamline care delivery, enhancing efficiency and accessibility. • Telepsychiatry bridges gaps in mental health services, catering to remote patients. • Teleeducation empowers nurses through accessible and flexible professional development.
Anticancer Potential of <i>Moringa oleifera</i> on BRCA-1 Gene: Systems Biology
Breast cancer has consistently been a global challenge that is prevalent among women. There is a continuous increase in the high number of women mortality rates because of breast cancer and affecting nations at all modernization levels. Women with high-risk factors, including hereditary, obesity, and menopause, have the possibility of developing breast cancer growth. With the advent of radiotherapy, chemotherapy, hormone therapy, and surgery in breast cancer treatment, breast cancer survivors have increased. Also, the design and development of drugs targeting therapeutic enzymes effectively treat the tumour cells early. However, long-term use of anticancer drugs has been linked to severe side effects. This research aims to develop potential drug candidates from Moringa oleifera, which could serve as anticancer agents. In silico analysis using Schrödinger Molecular Drug Discovery Suite and SWISS ADME was employed to determine the therapeutic potential of phytochemicals from M oleifera against breast cancer via molecular docking, pharmacokinetic parameters, and drug-like properties. The result shows that rutin, vicenin-2, and quercetin-3-O-glucoside have the highest binding energy of −7.522, −6.808, and −6.635 kcal/mol, respectively, in the active site of BRCA-1. The essential amino acids involved in the protein-ligand interaction following active site analysis are ASN 1678, ASN 1774, GLY 1656, LEU 1657, GLN 1779, LYS 1702, SER 1655, PHE 1662, ARG 1699, GLU 1698, and VAL 1654. Thus, we propose that bioactive compounds from M oleifera may be potential novel drug candidates in the treatment of breast cancer.
EFFECT OF COMPUTER-ASSISTED INSTRUCTION AND SIMULATION/GAMES ON THE ACADEMIC ACHIEVEMENT OF SECONDARY SCHOOL STUDENTS IN BIOLOGY
This study investigated the effect of Computer Assisted Instruction (CAI), Simulation/Games and Conventional Methods on the academic achievement of students in Biology. The treatment at the three levels of CAI, Simulation/Games and Conventional Method was crossed with gender at the two levels of male and female, and locus of control, at the two levels of internals and externals. Data analysis involved Analysis of Covariance as well as Multiple Classification Analysis as a post-hoc measure. The findings revealed no significant two-way and three-way interactions of treatment and gender and locus of control. However, there were significant main effects of treatment and locus of control on students’ achievement in Biology. The MCA further revealed that students taught with the Computer-Assisted Instruction achieved highest while students taught with Simulation/Games achieved better and those students taught with the Conventional Method had the lowest adjusted post-test mean score. Based on these findings, the use of Computer Instruction and Simulation/Games are recommended for teachers in Biology classrooms irrespective of the students’ gender and locus of control. The government is further enjoined to provide computers, programs, instructional packages, costumes and enabling environment for the use of these instructional strategies in schools.