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Research institution

University of Ilorin

NG

10 researchers0 verified6 linked papers164 indexed citations

Researchers

Public research profiles associated with University of Ilorin.

Research from this institution

Publications linked through researcher authorship records.

2020 · mSphere · 38 citations

Comparative Molecular Biology Approaches for the Production of Poliovirus Virus-Like Particles Using <i>Pichia pastoris</i>

Although the current poliovirus immunization program has been extremely successful in reducing the number of cases of paralytic polio worldwide, now more cases are caused by vaccine-derived polioviruses than by wild poliovirus. Switching to inactivated poliovirus vaccines will reduce this over time; however, their production requires the growth of large amounts of virus. This biosafety concern can be addressed by producing just the virus capsid. The capsid serves to protect the genetic material, which causes disease when introduced into a cell. Therefore, empty capsids (virus-like particles [VLPs]), which lack the viral RNA genome, are safe both to make and to use. We exploit yeast as a versatile model expression system to produce VLPs, and here we specifically highlight the potential of this system to supply next-generation poliovirus vaccines to secure a polio-free world for the future.

2014 · PLoS Computational Biology · 34 citations

Computational Biology and Bioinformatics in Nigeria

Over the past few decades, major advances in the field of molecular biology, coupled with advances in genomic technologies, have led to an explosive growth in the biological data generated by the scientific community. The critical need to process and analyze such a deluge of data and turn it into useful knowledge has caused bioinformatics to gain prominence and importance. Bioinformatics is an interdisciplinary research area that applies techniques, methodologies, and tools in computer and information science to solve biological problems. In Nigeria, bioinformatics has recently played a vital role in the advancement of biological sciences. As a developing country, the importance of bioinformatics is rapidly gaining acceptance, and bioinformatics groups comprised of biologists, computer scientists, and computer engineers are being constituted at Nigerian universities and research institutes. In this article, we present an overview of bioinformatics education and research in Nigeria. We also discuss professional societies and academic and research institutions that play central roles in advancing the discipline in Nigeria. Finally, we propose strategies that can bolster bioinformatics education and support from policy makers in Nigeria, with potential positive implications for other developing countries.

2017 · Cypriot Journal of Educational Sciences · 24 citations

Effects of computer animation instructional package on students’ achievement in practical biology

This study examined the effects of computer animation instructional package on secondary school students’ achievement in practical biology in Ilorin, Nigeria. The study adopted a pre-test, post-test, control group, non-randomised and nonequivalent quasi-experimental design, with a 2x2x3 factorial design. Two intact classes from two secondary schools were purposively sampled. The instruments used were Biology Practical Achievement Test (BPAT) for data gathering and Computer Animation Instructional Package (CAIP) as the treatment instrument. The reliability coefficient of BPAT was determined using the Pearson Product Moment Correlation and was found to be 0.91. Two research questions and two hypotheses were formulated in the study. The hypotheses were tested with t-test statistics at a significance level of 0.05. The study concluded that CAIP significantly improved students' achievement in practical biology. The researchers recommend that biology teachers should employ computer animation instructional packages to teach the practical aspects of photosynthesis among other biology topics. Keywords: Achievement, computer animation, practical biology, secondary schoo

2023 · Tropical Journal of Natural Product Research · 14 citations

Cancer Biology and Therapeutics: Navigating Recent Advances and Charting Future Directions

Cancer, a multifaceted and heterogeneous ailment, persists as a substantial global public health concern. Recent strides in cancer biology have profoundly augmented our comprehension of the intricate genetic and molecular mechanisms underlying the inception and advancement of cancer. This headway has propelled the formulation of innovative therapeutic strategies, embracing targeted interventions and immunotherapies, which have showcased promising outcomes in clinical assessments. However, a multitude of obstacles continue to challenge the creation of efficacious and individualized cancer treatments. This systematic review encapsulates an extensive vista of contemporary advancements in cancer biology and therapeutics, accentuating pivotal breakthroughs in our grasp of cancer's intricacies, while illuminating the latest therapeutic avenues for cancer management. Moreover, the paper elaborates on the quest's upcoming trajectories in cancer research and treatment, encompassing burgeoning technologies and uncharted domains of inquiry that might pave the way for more efficacious and personalized interventions for individuals afflicted by cancer.

2022 · JPBI (Jurnal Pendidikan Biologi Indonesia) · 14 citations

Influence of teachers’ self-efficacy on secondary school students’ self-efficacy in biology in Ogbomoso, Nigeria

It is widely proven by several studies that efficacy is an important factor in the teaching-learning process. Therefore, the goal of this study was to examine whether teachers’ self-efficacy contributes to the development of students’ self-efficacy in Biology. This study was a descriptive research with survey type which used proportionate and stratified sampling techniques to select 98 secondary schools in Ogbomoso, Nigeria. Proportionate, purposive, and simple random sampling techniques were used to select 207 biology teachers and 392 SSS I and II biology students based on gender. The data collected were analysed using mean scores, chi-square, and regression analysis at 0.05 level of significance. The findings revealed that: 1) there was a positive correlation between teachers’ self-efficacy and students’ self-efficacy in biology; 2) the level of teachers’ self-efficacy was moderately high; and 3) female students have higher self-efficacy than male students in biology. The study concluded that teachers’ self-efficacy influences their students’ self-efficacy. Thus, it is recommended that biology teachers should be responsible and pay more attention to the development of their students’ self-efficacy irrespective of students’ gender.