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University of Ottawa
CA
3 researchers0 verified3 linked papers29,727 indexed citations
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2000 · 18,110 citations
Structural equation modeling with AMOS: basic concepts, applications, and programming
Contents: Part I: Introduction. Structural Equation Models: The Basics. Using the EQS Program. Part II: Single-Group Analyses. Application 1: Testing for the Factorial Validity of a Theoretical Construct (First-Order CFA Model). Application 2: Testing for the Factorial Validity of Scores From a Measuring Instrument (First-Order CFA Model). Application 3: Testing for the Factorial Validity of Scores from a Measuring Instrument (Second-Order CFA Model). Application 4: Testing for the Validity of a Causal Structure. Part III: Multiple-Group Analyses. Application 5: Testing for the Factorial Invariance of a Measuring Instrument. Application 6: Testing for the Invariance of a Causal Structure. Application 7: Testing for Latent Mean Differences (First-Order CFA Model). Application 8: Testing for Latent Mean Differences (Second-Order CFA Model). Part IV: Other Important Topics. Application 9: Testing for Construct Validity: The Multitrait-Multimethod Model. Application 10: Testing for Change Over Time: The Latent Growth Curve Model. Application 11: Testing for Within- and Between-Level Variance: The Multilevel Model.
2020 · British Journal of Sports Medicine · 11,486 citations
World Health Organization 2020 guidelines on physical activity and sedentary behaviour
Objectives To describe new WHO 2020 guidelines on physical activity and sedentary behaviour. Methods The guidelines were developed in accordance with WHO protocols. An expert Guideline Development Group reviewed evidence to assess associations between physical activity and sedentary behaviour for an agreed set of health outcomes and population groups. The assessment used and systematically updated recent relevant systematic reviews; new primary reviews addressed additional health outcomes or subpopulations. Results The new guidelines address children, adolescents, adults, older adults and include new specific recommendations for pregnant and postpartum women and people living with chronic conditions or disability. All adults should undertake 150–300 min of moderate-intensity, or 75–150 min of vigorous-intensity physical activity, or some equivalent combination of moderate-intensity and vigorous-intensity aerobic physical activity, per week. Among children and adolescents, an average of 60 min/day of moderate-to-vigorous intensity aerobic physical activity across the week provides health benefits. The guidelines recommend regular muscle-strengthening activity for all age groups. Additionally, reducing sedentary behaviours is recommended across all age groups and abilities, although evidence was insufficient to quantify a sedentary behaviour threshold. Conclusion These 2020 WHO guidelines update previous WHO recommendations released in 2010. They reaffirm messages that some physical activity is better than none, that more physical activity is better for optimal health outcomes and provide a new recommendation on reducing sedentary behaviours. These guidelines highlight the importance of regularly undertaking both aerobic and muscle strengthening activities and for the first time, there are specific recommendations for specific populations including for pregnant and postpartum women and people living with chronic conditions or disability. These guidelines should be used to inform national health policies aligned with the WHO Global Action Plan on Physical Activity 2018–2030 and to strengthen surveillance systems that track progress towards national and global targets.
2021 · Biological reviews/Biological reviews of the Cambridge Philosophical Society · 131 citations
The naked truth: a comprehensive clarification and classification of current ‘myths’ in naked mole‐rat biology
The naked mole-rat (Heterocephalus glaber) has fascinated zoologists for at least half a century. It has also generated considerable biomedical interest not only because of its extraordinary longevity, but also because of unusual protective features (e.g. its tolerance of variable oxygen availability), which may be pertinent to several human disease states, including ischemia/reperfusion injury and neurodegeneration. A recent article entitled 'Surprisingly long survival of premature conclusions about naked mole-rat biology' described 28 'myths' which, those authors claimed, are a 'perpetuation of beautiful, but falsified, hypotheses' and impede our understanding of this enigmatic mammal. Here, we re-examine each of these 'myths' based on evidence published in the scientific literature. Following Braude et al., we argue that these 'myths' fall into four main categories: (i) 'myths' that would be better described as oversimplifications, some of which persist solely in the popular press; (ii) 'myths' that are based on incomplete understanding, where more evidence is clearly needed; (iii) 'myths' where the accumulation of evidence over the years has led to a revision in interpretation, but where there is no significant disagreement among scientists currently working in the field; (iv) 'myths' where there is a genuine difference in opinion among active researchers, based on alternative interpretations of the available evidence. The term 'myth' is particularly inappropriate when applied to competing, evidence-based hypotheses, which form part of the normal evolution of scientific knowledge. Here, we provide a comprehensive critical review of naked mole-rat biology and attempt to clarify some of these misconceptions.