TY  - JOUR
TI  - Fluorine in medicinal chemistry
AU  - Sophie Purser
AU  - Peter R. Moore
AU  - Steve Swallow
AU  - Véronique Gouverneur
PY  - 2007
JO  - Chemical Society Reviews
DO  - 10.1039/b610213c
UR  - https://doi.org/10.1039/b610213c
AB  - It has become evident that fluorinated compounds have a remarkable record in medicinal chemistry and will play a continuing role in providing lead compounds for therapeutic applications. This tutorial review provides a sampling of renowned fluorinated drugs and their mode of action with a discussion clarifying the role and impact of fluorine substitution on drug potency.
ER  -