Research institution
AstraZeneca (United Kingdom)
GB
2 researchers0 verified1 linked papers7,501 indexed citations
Researchers
Public research profiles associated with AstraZeneca (United Kingdom).
Research from this institution
Publications linked through researcher authorship records.
2007 · Chemical Society Reviews · 7,501 citations
Fluorine in medicinal chemistry
It has become evident that fluorinated compounds have a remarkable record in medicinal chemistry and will play a continuing role in providing lead compounds for therapeutic applications. This tutorial review provides a sampling of renowned fluorinated drugs and their mode of action with a discussion clarifying the role and impact of fluorine substitution on drug potency.