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Fluorine in Organic Chemistry, Synthesis and Biological Evaluation, Synthesis and Reactions of Organic Compounds

Fluorine in medicinal chemistry

Chemical Society Reviews · 2007

SSophie Purser·PPeter R. Moore·SSteve Swallow·VVéronique Gouverneur
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Abstract

It has become evident that fluorinated compounds have a remarkable record in medicinal chemistry and will play a continuing role in providing lead compounds for therapeutic applications. This tutorial review provides a sampling of renowned fluorinated drugs and their mode of action with a discussion clarifying the role and impact of fluorine substitution on drug potency.

Research topics

Fluorine in Organic ChemistrySynthesis and Biological EvaluationSynthesis and Reactions of Organic Compounds
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