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Fluorine in medicinal chemistry
2007 · Chemical Society Reviews · DOI 10.1039/b610213c
It has become evident that fluorinated compounds have a remarkable record in medicinal chemistry and will play a continuing role in providing lead compounds for therapeutic applications. This tutorial review provides a sampling of renowned fluorinated drugs and their mode of action with a discussion clarifying the role and impact of fluorine substitution on drug potency.
Read paperCo-authors
Sophie Purser
Mansfield University
1 shared publicationPeter R. Moore
AstraZeneca (United Kingdom)
1 shared publicationVéronique Gouverneur
Mansfield University
1 shared publication