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Awoke Misganaw Temesgen

· University of Washington

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Awoke Misganaw Temesgen is a registered researcher in their academic field.

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Cardiovascular Health and Risk Factors, Global Public Health Policies and Epidemiology, Blood Pressure and Hypertension Studies · 2020 · Journal of the American College of Cardiology

Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019

Gregory A. Roth, George A. Mensah, Catherine O. Johnson, Giovanni Addolorato, Enrico Ammirati, Larry M. Baddour, Noël C. Barengo, Andrea Beaton, Emelia J. Benjamin, Catherine P. Benziger, Aimé Bonny, Michael Bräuer, Marianne Brodmann, Thomas J. Cahill, Jonathan R. Carapetis, Alberico L. Catapano, Sumeet S. Chugh, Leslie T. Cooper, Josef Coresh, Michael H Criqui, Nicole DeCleene, Kim A. Eagle, Sophia Emmons‐Bell, Valery L. Feigin, Joaquim Fernández‐Solà, Gerry Fowkes, Emmanuela Gakidou, Scott M. Grundy, Feng J. He, George Howard, Frank B. Hu, Lesley A. Inker, Ganesan Karthikeyan, Nicholas J Kassebaum, Walter J. Koroshetz, Carl J. Lavie, Donald M. Lloyd‐Jones, Hong Lü, Antonio Mirijello, Awoke Misganaw Temesgen, Ali H. Mokdad, Andrew Moran, Paul Muntner, Jagat Narula, Bruce Neal, Mpiko Ntsekhe, Glaucia Moraes de Oliveira, Catherine M Otto, Mayowa Owolabi, Michael Pratt, Sanjay Rajagopalan, Marissa B Reitsma, Antônio Luiz Pinho Ribeiro, Nancy A. Rigotti, Anthony Rodgers, Craig Sable, Saate Shakil, Karen Sliwa‐Hahnle, Benjamin Stark, Johan Sundström, Patrick Timpel, Imad M. Tleyjeh, Marco Valgimigli, Theo Vos, Paul K. Whelton, Magdi Yacoub, Liesl Zühlke, Chris Murray, Valentı́n Fuster, F. Gerry R. Fowkes

Cardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability. This paper reviews the magnitude of total CVD burden, including 13 underlying causes of cardiovascular death and 9 related risk factors, using estimates from the Global Burden of Disease (GBD) Study 2019. GBD, an ongoing multinational collaboration to provide comparable and consistent estimates of population health over time, used all available population-level data sources on incidence, prevalence, case fatality, mortality, and health risks to produce estimates for 204 countries and territories from 1990 to 2019. Prevalent cases of total CVD nearly doubled from 271 million (95% uncertainty interval [UI]: 257 to 285 million) in 1990 to 523 million (95% UI: 497 to 550 million) in 2019, and the number of CVD deaths steadily increased from 12.1 million (95% UI:11.4 to 12.6 million) in 1990, reaching 18.6 million (95% UI: 17.1 to 19.7 million) in 2019. The global trends for disability-adjusted life years (DALYs) and years of life lost also increased significantly, and years lived with disability doubled from 17.7 million (95% UI: 12.9 to 22.5 million) to 34.4 million (95% UI:24.9 to 43.6 million) over that period. The total number of DALYs due to IHD has risen steadily since 1990, reaching 182 million (95% UI: 170 to 194 million) DALYs, 9.14 million (95% UI: 8.40 to 9.74 million) deaths in the year 2019, and 197 million (95% UI: 178 to 220 million) prevalent cases of IHD in 2019. The total number of DALYs due to stroke has risen steadily since 1990, reaching 143 million (95% UI: 133 to 153 million) DALYs, 6.55 million (95% UI: 6.00 to 7.02 million) deaths in the year 2019, and 101 million (95% UI: 93.2 to 111 million) prevalent cases of stroke in 2019. Cardiovascular diseases remain the leading cause of disease burden in the world. CVD burden continues its decades-long rise for almost all countries outside high-income countries, and alarmingly, the age-standardized rate of CVD has begun to rise in some locations where it was previously declining in high-income countries. There is an urgent need to focus on implementing existing cost-effective policies and interventions if the world is to meet the targets for Sustainable Development Goal 3 and achieve a 30% reduction in premature mortality due to noncommunicable diseases.

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Injury Epidemiology and Prevention, Trauma and Emergency Care Studies, Autopsy Techniques and Outcomes · 2015 · Injury Prevention

The global burden of injury: incidence, mortality, disability-adjusted life years and time trends from the Global Burden of Disease study 2013

Juanita A. Haagsma, Nicholas Graetz, Ian Bolliger, Mohsen Naghavi, Hideki Higashi, Erin C Mullany, Semaw Ferede Abera, Jerry Abraham, Adofo Koranteng, Ubai Alsharif, Emmanuel A Ameh, Walid Ammar, Carl Abelardo T. Antonio, Lope H. Barrero, Tolesa Bekele, Dipan Bose, Alexandra Bražinová, Ferrán Catalá-López, Lalit Dandona, Rakhi Dandona, Paul I. Dargan, Diego De Leo, Louisa Degenhardt, Sarah Derrett, Samath Dhamminda Dharmaratne, Tim Driscoll, Leilei Duan, Ermakov Sp, Farshad Farzadfar, Valery L. Feigin, Richard C. Franklin, Belinda J. Gabbe, Richard A. Gosselin, Nima Hafezi‐Nejad, Randah R Hamadeh, Martha Hı́jar, Guoqing Hu, Sudha Jayaraman, Guohong Jiang, Yousef Khader, Ejaz Ahmad Khan, Sanjay Krishnaswami, Chanda Kulkarni, Fiona Lecky, Ricky Leung, Raimundas Lunevičius, Ronan A Lyons, Marek Majdán, Amanda J. Mason‐Jones, Richard Matzopoulos, Peter A. Meaney, Wubegzier Mekonnen, Ted R. Miller, Charles Mock, Rosana Norman, Ricardo Orozco, Suzanne Polinder, Farshad Pourmalek, Vafa Rahimi‐Movaghar, Amany Refaat, David Rojas‐Rueda, Nobhojit Roy, David C. Schwebel, Amira Shaheen, Saeid Shahraz, Vegard Skirbekk, Kjetil Søreide, Sergey Soshnikov, Dan J. Stein, Bryan L. Sykes, Karen M. Tabb, Awoke Misganaw Temesgen, Eric Y. Tenkorang, Alice Theadom, Bach Xuan Tran, Tommi Vasankari, Monica S. Vavilala, Vasily Vlassov, Solomon Woldeyohannes, Paul Yip, Naohiro Yonemoto, Mustafa Z Younis, Chuanhua Yu, Christopher Murray, Theo Vos, Shivanthi Balalla, Michael Phillips

BACKGROUND: The Global Burden of Diseases (GBD), Injuries, and Risk Factors study used the disability-adjusted life year (DALY) to quantify the burden of diseases, injuries, and risk factors. This paper provides an overview of injury estimates from the 2013 update of GBD, with detailed information on incidence, mortality, DALYs and rates of change from 1990 to 2013 for 26 causes of injury, globally, by region and by country. METHODS: Injury mortality was estimated using the extensive GBD mortality database, corrections for ill-defined cause of death and the cause of death ensemble modelling tool. Morbidity estimation was based on inpatient and outpatient data sets, 26 cause-of-injury and 47 nature-of-injury categories, and seven follow-up studies with patient-reported long-term outcome measures. RESULTS: In 2013, 973 million (uncertainty interval (UI) 942 to 993) people sustained injuries that warranted some type of healthcare and 4.8 million (UI 4.5 to 5.1) people died from injuries. Between 1990 and 2013 the global age-standardised injury DALY rate decreased by 31% (UI 26% to 35%). The rate of decline in DALY rates was significant for 22 cause-of-injury categories, including all the major injuries. CONCLUSIONS: Injuries continue to be an important cause of morbidity and mortality in the developed and developing world. The decline in rates for almost all injuries is so prominent that it warrants a general statement that the world is becoming a safer place to live in. However, the patterns vary widely by cause, age, sex, region and time and there are still large improvements that need to be made.

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