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Xiaochen Dai

· University of Washington

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Xiaochen Dai is a registered researcher in their academic field.

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3 research works linked to this profile

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Ophthalmology and Visual Impairment Studies, Tactile and Sensory Interactions, Retinopathy of Prematurity Studies · 2020 · The Lancet Global Health

Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study

Rupert Bourne, Jaimie D Steinmetz, Seth Flaxman, Paul Svitil Briant, Hugh R. Taylor, Serge Resnikoff, Robert J. Casson, Amir Abdoli, Eman Abu‐Gharbieh, Ashkan Afshin, Hamid Ahmadieh, Yonas Akalu, Alehegn Aderaw Alamneh, Wondu Alemayehu, Ahmed Samir Alfaar, Vahid Alipour, Etsay Woldu Anbesu, Sofia Androudi, Jalal Arabloo, Aries Arditi, Malke Asaad, Eleni Bagli, Atif Amin Baig, Till Bärnighausen, Maurízio Battaglia Parodi, Akshaya Srikanth Bhagavathula, Nikha Bhardwaj, Pankaj Bhardwaj, Krittika Bhattacharyya, Ali Bijani, Mukharram M. Bikbov, Michele Bottone, Tasanee Braithwaite, Alain M. Bron, Zahid A Butt, Ching‐Yu Cheng, Dinh‐Toi Chu, Maria Vittoria Cicinelli, João Coelho, Baye Dagnew, Xiaochen Dai, Reza Dana, Lalit Dandona, Rakhi Dandona, Monte A. Del Monte, Jenny P Deva, Daniel Díaz, Shirin Djalalinia, Laura E. Dreer, Joshua R. Ehrlich, Leon B. Ellwein, Mohammad Hassan Emamian, Arthur Gustavo Fernandes, Florian Fischer, David S. Friedman, João M. Furtado, Abhay Gaidhane, Shilpa Gaidhane, Gus Gazzard, Berhe Gebremichael, Ronnie George, Ahmad Ghashghaee, Mahaveer Golechha, Samer Hamidi, Billy R. Hammond, M. Elizabeth Hartnett, Risky Kusuma Hartono, Simon I Hay, Golnaz Heidari, Hung Chak Ho, Chi Linh Hoang, Mowafa Househ, Segun Emmanuel Ibitoye, Irena Ilić, Milena Ilić, April Ingram, Seyed Sina Naghibi Irvani, Ravi Prakash Jha, Rim Kahloun, Himal Kandel, Ayele Semachew Kasa, John H. Kempen, Maryam Keramati, Moncef Khairallah, Ejaz Ahmad Khan, Rohit C Khanna, Mahalaqua Nazli Khatib, Judy E. Kim, Yun Jin Kim, Sezer Kısa, Adnan Kısa, Ai Koyanagi, Om Kurmi, Van Charles Lansingh, Janet L Leasher, Nicolas Leveziel, Hans Limburg, Marek Majdán, Navid Manafi, Kaweh Mansouri

Background To contribute to the WHO initiative, VISION 2020: The Right to Sight, an assessment of global vision impairment in 2020 and temporal change is needed. We aimed to extensively update estimates of global vision loss burden, presenting estimates for 2020, temporal change over three decades between 1990–2020, and forecasts for 2050. Methods We did a systematic review and meta-analysis of population-based surveys of eye disease from January, 1980, to October, 2018. Only studies with samples representative of the population and with clearly defined visual acuity testing protocols were included. We fitted hierarchical models to estimate 2020 prevalence (with 95% uncertainty intervals [UIs]) of mild vision impairment (presenting visual acuity ≥6/18 and

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Ophthalmology and Visual Impairment Studies, Tactile and Sensory Interactions, Retinopathy of Prematurity Studies · 2020 · The Lancet Global Health

Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study

Jaimie D Steinmetz, Rupert Bourne, Paul Svitil Briant, Seth Flaxman, Hugh R B Taylor, Jost B. Jonas, Amir Abdoli, Woldu Aberhe Abrha, Ahmed Abualhasan, Eman Girum Abu-Gharbieh, Tadele Girum Girum Adal, Ashkan Afshin, Hamid Ahmadieh, Wondu Alemayehu, Sayyed Amirpooya Alemzadeh, Ahmed Samir Alfaar, Vahid Alipour, Sofia Androudi, Jalal Arabloo, Aries Arditi, Brhane Berhe Aregawi, Alessandro Arrigo, Charlie Ashbaugh, Elham Ashrafi, Desta Debalkie Atnafu, Eleni Bagli, Atif Amin Baig, Till Bärnighausen, Maurízio Battaglia Parodi, Mahya Beheshti, Akshaya Srikanth Bhagavathula, Nikha Bhardwaj, Pankaj Bhardwaj, Krittika Bhattacharyya, Ali Bijani, Mukharram M. Bikbov, Michele Bottone, Tasanee M Braithwaite, Alain M. Bron, Sharath Burugina Nagaraja, Zahid A Butt, Florentino Luciano Caetano dos Santos, Vera Lúcia Alves Carneiro, Robert J. Casson, Ching-Yu Jasmine Cheng, Jee-Young Jasmine Choi, Dinh‐Toi Chu, Maria Vittoria Cicinelli, João M G Coelho, Nathan Congdon, Rosa A A Couto, Elizabeth A. Cromwell, Saad M A Dahlawi, Xiaochen Dai, Reza Dana, Lalit Dandona, Rakhi Dandona, Monte A. Del Monte, Meseret Derbew Molla, Nikolaos Dervenis, Abebaw Alemayehu Desta, Jenny P Deva, Daniel Díaz, Shirin E Djalalinia, Joshua R. Ehrlich, Rajesh Elayedath, Hala Rashad Elhabashy, Leon B. Ellwein, Mohammad Hassan Emamian, Sharareh Eskandarieh, Farshad Farzadfar, Arthur Gustavo Fernandes, Florian Fischer, David S. Friedman, João M. Furtado, Shilpa Gaidhane, Gus Gazzard, Berhe Gebremichael, Ronnie George, Ahmad Ghashghaee, Syed Amir Gilani, Mahaveer Golechha, Samer Randall Hamidi, Billy R. Hammond, M. Elizabeth Hartnett, Risky Kusuma Hartono, Abdiwahab Hashi, Simon I Hay, Khezar Hayat, Golnaz Heidari, Hung Chak Ho, Ramesh Holla, Mowafa J Househ, John J. Huang, Segun Emmanuel Ibitoye, Irena Ilić, Milena Ilić, April Ingram, Seyed Sina Naghibi Irvani, Sheikh Mohammed Shariful Islam

BACKGROUND: Many causes of vision impairment can be prevented or treated. With an ageing global population, the demands for eye health services are increasing. We estimated the prevalence and relative contribution of avoidable causes of blindness and vision impairment globally from 1990 to 2020. We aimed to compare the results with the World Health Assembly Global Action Plan (WHA GAP) target of a 25% global reduction from 2010 to 2019 in avoidable vision impairment, defined as cataract and undercorrected refractive error. METHODS: We did a systematic review and meta-analysis of population-based surveys of eye disease from January, 1980, to October, 2018. We fitted hierarchical models to estimate prevalence (with 95% uncertainty intervals [UIs]) of moderate and severe vision impairment (MSVI; presenting visual acuity from

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Smoking Behavior and Cessation, Health disparities and outcomes, Health, Environment, Cognitive Aging · 2017 · The Lancet

Smoking prevalence and attributable disease burden in 195 countries and territories, 1990–2015: a systematic analysis from the Global Burden of Disease Study 2015

Marissa B Reitsma, Nancy Fullman, Marie Ng, Joseph S Salama, Amanuel Alemu Abajobir, Kalkidan Hassen Abate, Cristiana Abbafati, Semaw Ferede Abera, Biju Abraham, Gebre Yitayih Abyu, Akindele O. Adebiyi, Ziyad Al‐Aly, Alicia V Aleman, Raghib Ali, Ala’a Alkerwi, Peter Allebeck, Rajaa Al‐Raddadi, Azmeraw T. Amare, Alemayehu Amberbir, Walid Ammar, Stephen M. Amrock, Carl Abelardo T. Antonio, Hamid Asayesh, Niguse Tadela Atnafu, Peter Azzopardi, Amitava Banerjee, Aleksandra Barać, Tonatiuh Barrientos‐Gutiérrez, Ana Basto‐Abreu, Shahrzad Bazargan‐Hejazi, Neeraj Bedi, Brent Bell, Aminu K. Bello, Isabela M. Benseñor, Addisu Shunu Beyene, Neeraj Bhala, Stan Biryukov, Kaylin Bolt, Hermann Brenner, Zahid A Butt, Fiorella Cavalleri, Kelly Cercy, Honglei Chen, Devasahayam Jesudas Christopher, Liliana G Ciobanu, Valentina Colistro, Mercedes Colomar, Leslie Cornaby, Xiaochen Dai, Solomon Abrha Damtew, Lalit Dandona, Rakhi Dandona, Emily Dansereau, Kairat Davletov, Anand Dayama, Tizta Tilahun Degfie, Amare Deribew, Samath Dhamminda Dharmaratne, Balem Dimtsu, Kerrie Doyle, Aman Yesuf Endries, Sergey Petrovich Ermakov, Kara Estep, Emerito Jose A Faraon, Farshad Farzadfar, Valery L. Feigin, Andrea B Feigl, Florian Fischer, Joseph Friedman, Tsegaye Tewelde G/hiwot, Seana Gall, Wayne Gao, Richard F Gillum, Audra L Gold, Sameer Vali Gopalani, Carolyn Gotay, Rahul Gupta, Rajeev Gupta, Vipin Gupta, Randah R Hamadeh, Graeme J. Hankey, Hilda L Harb, Simon I Hay, Masako Horino, Nobuyuki Horita, Hung Chak Ho, Abdullatif Husseini, Bogdan Vasile Ileanu, Farhad Islami, Guohong Jiang, Ying Jiang, Jost B. Jonas, Zubair Kabir, Ritul Kamal, Amir Kasaeian, Chandrasekharan Nair Kesavachandran, Yousef Khader, Ibrahim Khalil, Young‐Ho Khang, Sahil Khera

BACKGROUND: The scale-up of tobacco control, especially after the adoption of the Framework Convention for Tobacco Control, is a major public health success story. Nonetheless, smoking remains a leading risk for early death and disability worldwide, and therefore continues to require sustained political commitment. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) offers a robust platform through which global, regional, and national progress toward achieving smoking-related targets can be assessed. METHODS: We synthesised 2818 data sources with spatiotemporal Gaussian process regression and produced estimates of daily smoking prevalence by sex, age group, and year for 195 countries and territories from 1990 to 2015. We analysed 38 risk-outcome pairs to generate estimates of smoking-attributable mortality and disease burden, as measured by disability-adjusted life-years (DALYs). We then performed a cohort analysis of smoking prevalence by birth-year cohort to better understand temporal age patterns in smoking. We also did a decomposition analysis, in which we parsed out changes in all-cause smoking-attributable DALYs due to changes in population growth, population ageing, smoking prevalence, and risk-deleted DALY rates. Finally, we explored results by level of development using the Socio-demographic Index (SDI). FINDINGS: Worldwide, the age-standardised prevalence of daily smoking was 25·0% (95% uncertainty interval [UI] 24·2-25·7) for men and 5·4% (5·1-5·7) for women, representing 28·4% (25·8-31·1) and 34·4% (29·4-38·6) reductions, respectively, since 1990. A greater percentage of countries and territories achieved significant annualised rates of decline in smoking prevalence from 1990 to 2005 than in between 2005 and 2015; however, only four countries had significant annualised increases in smoking prevalence between 2005 and 2015 (Congo [Brazzaville] and Azerbaijan for men and Kuwait and Timor-Leste for women). In 2015, 11·5% of global deaths (6·4 million [95% UI 5·7-7·0 million]) were attributable to smoking worldwide, of which 52·2% took place in four countries (China, India, the USA, and Russia). Smoking was ranked among the five leading risk factors by DALYs in 109 countries and territories in 2015, rising from 88 geographies in 1990. In terms of birth cohorts, male smoking prevalence followed similar age patterns across levels of SDI, whereas much more heterogeneity was found in age patterns for female smokers by level of development. While smoking prevalence and risk-deleted DALY rates mostly decreased by sex and SDI quintile, population growth, population ageing, or a combination of both, drove rises in overall smoking-attributable DALYs in low-SDI to middle-SDI geographies between 2005 and 2015. INTERPRETATION: The pace of progress in reducing smoking prevalence has been heterogeneous across geographies, development status, and sex, and as highlighted by more recent trends, maintaining past rates of decline should not be taken for granted, especially in women and in low-SDI to middle-SDI countries. Beyond the effect of the tobacco industry and societal mores, a crucial challenge facing tobacco control initiatives is that demographic forces are poised to heighten smoking's global toll, unless progress in preventing initiation and promoting cessation can be substantially accelerated. Greater success in tobacco control is possible but requires effective, comprehensive, and adequately implemented and enforced policies, which might in turn require global and national levels of political commitment beyond what has been achieved during the past 25 years. FUNDING: Bill & Melinda Gates Foundation and Bloomberg Philanthropies.