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James Harvey

· University of Washington

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James Harvey is a registered researcher in their academic field.

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COVID-19 and healthcare impacts, Economic and Financial Impacts of Cancer, Global Cancer Incidence and Screening · 2021 · JAMA Oncology

Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019

Jonathan Kocarnik, Kelly Compton, Frances Dean, Weijia Fu, Brian Gaw, James Harvey, Hannah Henrikson, Dan Lu, Alyssa Pennini, Rixing Xu, Emad Ababneh, Mohsen Abbasi‐Kangevari, Hedayat Abbastabar, Sherief Abd‐Elsalam, Amir Abdoli, Aidin Abedi, Hassan Abidi, Hassan Abolhassani, Isaac Akinkunmi Adedeji, Qorinah Estiningtyas Sakilah Adnani, Shailesh M Advani, Muhammad U. Afzal, Mohammad Aghaali, Bright Opoku Ahinkorah, Sajjad Ahmad, Tauseef Ahmad, Ali Ahmadi, Sepideh Ahmadi, Tarik A. Rashid, Yusra Ahmed Salih, Gizachew Taddesse Akalu, Addis Aklilu, Tayyaba Akram, Chisom Joyqueenet Akunna, Hanadi Al Hamad, Fares Alahdab, Ziyad Al‐Aly, Saqib Ali, Yousef Alimohamadi, Vahid Alipour, Syed Mohamed Aljunid, Motasem Alkhayyat, Amir Almasi‐Hashiani, Nihad A. Almasri, Sadeq Ali Al‐Maweri, Sami Almustanyir, Nivaldo Alonso, Nelson Alvis‐Guzmán, Hubert Amu, Etsay Woldu Anbesu, Robert Ancuceanu, Fereshteh Ansari, Alireza Ansari‐Moghaddam, Maxwell Hubert Antwi, Davood Anvari, Anayochukwu Edward Anyasodor, Muhammad Aqeel, Jalal Arabloo, Morteza Arab‐Zozani, Olatunde Aremu, Hany Ariffin, Timur Aripov, Muhammad Arshad, Al Artaman, Judie Arulappan, Zatollah Asemi, Mohammad Asghari Jafarabadi, Tahira Ashraf, Prince Atorkey, Avinash Aujayeb, Marcel Ausloos, Atalel Fentahun Awedew, Beatriz Paulina Ayala Quintanilla, Temesgen Ayenew, Mohammed A. Azab, Sina Azadnajafabad, Amirhossein Azari Jafari, Ghasem Azarian, Ahmed Y. Azzam, Ashish Badiye, Saeed Bahadory, Atif Amin Baig, Jennifer L. Baker, Senthilkumar Balakrishnan, Maciej Banach, Till Bärnighausen, Francesco Barone‐Adesi, Fabio Barra, Amadou Barrow, Masoud Behzadifar, Uzma Belgaumi, Woldesellassie Bezabhe, Yihienew Mequanint Bezabih, Devidas S. Bhagat, Akshaya Srikanth Bhagavathula, Nikha Bhardwaj, Pankaj Bhardwaj, Sonu Bhaskar, Krittika Bhattacharyya, Vijayalakshmi S Bhojaraja

IMPORTANCE: The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden. OBJECTIVE: To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic Index (SDI) quintiles from 2010 to 2019. EVIDENCE REVIEW: The GBD 2019 estimation methods were used to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life years (DALYs) in 2019 and over the past decade. Estimates are also provided by quintiles of the SDI, a composite measure of educational attainment, income per capita, and total fertility rate for those younger than 25 years. Estimates include 95% uncertainty intervals (UIs). FINDINGS: In 2019, there were an estimated 23.6 million (95% UI, 22.2-24.9 million) new cancer cases (17.2 million when excluding nonmelanoma skin cancer) and 10.0 million (95% UI, 9.36-10.6 million) cancer deaths globally, with an estimated 250 million (235-264 million) DALYs due to cancer. Since 2010, these represented a 26.3% (95% UI, 20.3%-32.3%) increase in new cases, a 20.9% (95% UI, 14.2%-27.6%) increase in deaths, and a 16.0% (95% UI, 9.3%-22.8%) increase in DALYs. Among 22 groups of diseases and injuries in the GBD 2019 study, cancer was second only to cardiovascular diseases for the number of deaths, years of life lost, and DALYs globally in 2019. Cancer burden differed across SDI quintiles. The proportion of years lived with disability that contributed to DALYs increased with SDI, ranging from 1.4% (1.1%-1.8%) in the low SDI quintile to 5.7% (4.2%-7.1%) in the high SDI quintile. While the high SDI quintile had the highest number of new cases in 2019, the middle SDI quintile had the highest number of cancer deaths and DALYs. From 2010 to 2019, the largest percentage increase in the numbers of cases and deaths occurred in the low and low-middle SDI quintiles. CONCLUSIONS AND RELEVANCE: The results of this systematic analysis suggest that the global burden of cancer is substantial and growing, with burden differing by SDI. These results provide comprehensive and comparable estimates that can potentially inform efforts toward equitable cancer control around the world.

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Global Cancer Incidence and Screening, Multiple and Secondary Primary Cancers, Cancer Risks and Factors · 2018 · JAMA Oncology

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2016

Christina Fitzmaurice, Tomi Akinyemiju, Faris Lami, Shazia Alam, Reza Alizadeh‐Navaei, Christine A. Allen, Ubai Alsharif, Nelson Alvis‐Guzmán, Erfan Amini, Benjamin O. Anderson, Olatunde Aremu, Al Artaman, Solomon Weldegebreal Asgedom, Reza Assadi, Tesfay Mehari Atey, Leticia Ávila‐Burgos, Ashish Awasthi, Huda Omer Ba Saleem, Aleksandra Barać, James R. Bennett, Isabela M. Benseñor, Nickhill Bhakta, Hermann Brenner, Lucero Cahuana-Hurtado, Carlos A Castañeda-Orjuela, Ferrán Catalá-López, Jee-Young J Choi, Devasahayam Jesudas Christopher, Sheng‐Chia Chung, María Paula Curado, Lalit Dandona, Rakhi Dandona, José das Neves, Subhojit Dey, Samath Dhamminda Dharmaratne, David Teye Doku, Tim Driscoll, Manisha Dubey, Hedyeh Ebrahimi, Dumessa Edessa, Ziad El‐Khatib, Aman Yesuf Endries, Florian Fischer, Lisa M Force, Kyle J Foreman, Solomon Weldemariam Gebrehiwot, Sameer Vali Gopalani, Giuseppe Grosso, Rahul Gupta, Bishal Gyawali, Randah R Hamadeh, Samer Hamidi, James Harvey, Hamid Yimam Hassen, Roderick J. Hay, Simon I Hay, Behzad Heibati, Molla Kahssay Hiluf, Nobuyuki Horita, Hung Chak Ho, Olayinka Stephen Ilesanmi, Kaire Innos, Farhad Islami, Mihajlo Jakovljević, Sarah Charlotte Johnson, Jost B Jonas, Amir Kasaeian, Tesfaye Kassa, Yousef Khader, Ejaz Ahmad Khan, Gulfaraz Khan, Young‐Ho Khang, Mohammad Hossein Khosravi, Jagdish Khubchandani, Jacek A Kopec, G Anil Kumar, Michael Kutz, Deepesh Lad, Alessandra Lafranconi, Qing Lan, Yirga Legesse, James Leigh, Shai Linn, Raimundas Lunevičius, Azeem Majeed, Reza Malekzadeh, Déborah Carvalho Malta, LG Mantovani, Brian J. McMahon, Toni Meier, Yohannes Adama Melaku, Mulugeta Melku, Peter Memiah, Walter Mendoza, Tuomo J Meretoja, Haftay Berhane Mezgebe, Ted R. Miller, Shafiu Mohammed, Ali H. Mokdad, Mahmood Moosazadeh

Importance: The increasing burden due to cancer and other noncommunicable diseases poses a threat to human development, which has resulted in global political commitments reflected in the Sustainable Development Goals as well as the World Health Organization (WHO) Global Action Plan on Non-Communicable Diseases. To determine if these commitments have resulted in improved cancer control, quantitative assessments of the cancer burden are required. Objective: To assess the burden for 29 cancer groups over time to provide a framework for policy discussion, resource allocation, and research focus. Evidence Review: Cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life-years (DALYs) were evaluated for 195 countries and territories by age and sex using the Global Burden of Disease study estimation methods. Levels and trends were analyzed over time, as well as by the Sociodemographic Index (SDI). Changes in incident cases were categorized by changes due to epidemiological vs demographic transition. Findings: In 2016, there were 17.2 million cancer cases worldwide and 8.9 million deaths. Cancer cases increased by 28% between 2006 and 2016. The smallest increase was seen in high SDI countries. Globally, population aging contributed 17%; population growth, 12%; and changes in age-specific rates, -1% to this change. The most common incident cancer globally for men was prostate cancer (1.4 million cases). The leading cause of cancer deaths and DALYs was tracheal, bronchus, and lung cancer (1.2 million deaths and 25.4 million DALYs). For women, the most common incident cancer and the leading cause of cancer deaths and DALYs was breast cancer (1.7 million incident cases, 535 000 deaths, and 14.9 million DALYs). In 2016, cancer caused 213.2 million DALYs globally for both sexes combined. Between 2006 and 2016, the average annual age-standardized incidence rates for all cancers combined increased in 130 of 195 countries or territories, and the average annual age-standardized death rates decreased within that timeframe in 143 of 195 countries or territories. Conclusions and Relevance: Large disparities exist between countries in cancer incidence, deaths, and associated disability. Scaling up cancer prevention and ensuring universal access to cancer care are required for health equity and to fulfill the global commitments for noncommunicable disease and cancer control.

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